Chronic Kidney Disease in HIV-Infected Patients

Publication Date: September 24, 2014

Key Points

Key Points

  • The risk of chronic kidney disease (CKD) is increased in individuals infected with human immunodeficiency virus (HIV) compared with the general population.
  • In African Americans, HIV infection imparts a risk for end-stage renal disease (ESRD) that is of similar magnitude to that of diabetes.
  • -infected patients, including direct effects by HIVA constellation of potential factors contributes to excess kidney disease in HIV-infected patients, including direct effects by HIV infection, HIV-associated immune activation, drug toxicity, coinfection with hepatitis C virus, and a high prevalence of traditional kidney disease risk factors.

Diagnosis

...agnosi...

...itoring

...monitoring creatinine-based estimated glomerula...

...onitoring kidney damage with urinaly...


Evaluati...

IDSA recommends that the evaluation of new-onset o...

...s that HIV-infected patients with kidn...

...IDSA recommends establishing permanent dialy...

...ossible, IDSA recommends avoiding the u...

...re 1. Chronic Kidney Disease Classificatio...

...1. Classification of Albuminuria and Proteinuri...

...able 2. Risk Factors for CKD and ESRD...

...Laboratory Indicators of Proximal...


Treatment

...atment...

Management

IDSA recommends that clinicians prescribe ART...

...mmends that clinicians use either the CKD Epi...

...ends that patients with biopsy-confirmed or c...

...patients infected with HIV who have a GFR...

...r-treated patients who experience a conf...


...vascular Drugs...

...ds using angiotensin-converting enzy...

...recommends that HIV-infected individ...

...A suggests that clinicians consider presc...


...ood Pressu...

IDSA recommends a target blood pressure...

...a target blood pressure of 30-300 mg/day...


...orticosteroids

IDSA suggests that clinicians conside...


...dney Transplantation...

...s that HIV providers assess patient...

...recommends that HIV providers assess patients...


Children and Adolescents with HIV

...d Adolescents with HIV...

...eening

...dults, IDSA recommends that children...

...voiding tenofovir as part of first-line the...


...eatment

...ends that children and adolescents with HIV who h...

...ts using ACE inhibitors or ARBs to treat proteinu...

...DSA suggests that corticosteroids NOT...

...ng of Antiretroviral Drugs for HIV-Infected Adul...